• Glutamate receptor internalization is thought to occur throu

  2020-07-30

  

  Glutamate receptor internalization is thought to occur through clathrin-mediated endocytosis Beattie et al. 2000, Carroll et al. 1999, Ehlers 2000, Lin et al. 2000, Man et al. 2000, Wang and Linden 2000, a general mechanism for the internalization of proteins from the plasma membrane (Mousavi et al.

• Following Duncan as a ritualized site

  2020-07-30

  

  Following Duncan (1995), as a ritualized site Tyne Cot provides an opportunity for individual tourists to conduct their own acts of remembrance (Edensor, 2000, Iles, 2006). The analysis has also shown that individual acts of writing particular words and phrases in the visitor books are socially shar

• Our results also suggest a

  2020-07-30

  

  Our results also suggest a relationship between the COMT rs4680 polymorphism and psychiatric symptomatology in epilepsy. As a group, Val carriers had higher scores on the Schizophrenia, Antisocial Features, and Alcohol Problems scales of the PAI than those without a Val allele. The Val allele has pr

• br Materials and methods br

  2020-07-30

  

  Materials and methods Results and discussion Discussion and conclusion TERRA G-quadruplexes are ideal therapeutic targets because they are required for telomere heterochromatin formation in all cancer cells, even in those that do not require telomerase (ALT-positive tumors). Several TERRA-b

• The results from this short

  2020-07-30

  

  The results from this short-term laboratory study corroborate the use of T-ChE and Es-ChE activity in gills and digestive gland (albeit, with higher control variance) of Saccostrea sp. as sensitive biomarkers of xenobiotic exposure. We show that a common organophosphate pesticide, chlorpyrifos, caus

• MKT 077 br Introduction Safety critical systems

  2020-07-29

  

  Introduction Safety-critical systems are defined as those systems where failure could result in the loss of life or injury to people, damage to equipment or to the environment [9]. Safety standards, e.g., [41], [17], [18], [6], [38], expect appropriate safety analysis tasks to be integrated withi

• Recently DDR has been reported to be capable

  2020-07-28

  

  Recently, DDR1 has been reported to be capable of inducing multiorgan site metastatic reactivation in breast cancer via noncanonical DDR1 signaling [40]. Consistent with this report, DDR1-silenced GC Zoniporide dihydrochloride were almost completely suppressed in our liver metastatic model. We found

• br DDR expression in inflammatory cells

  2020-07-28

  

  DDR1 expression in inflammatory cells Inflammatory irak inhibitor play a key role in the initiation and progression of the fibrotic lesion [35]. In the published literature very few groups have studied the expression and functions of DDR1 in inflammatory cells. This picture is further complicate

• In vertebrates PAH AhR CYP A

  2020-07-28

  

  In vertebrates, PAH-AhR-CYP1A axis has been well established. AhR-dependent transcriptional modulation is caused by the xenobiotic response crm1 (XRE) located on its promoter sequences (Jeong and Kim, 2002). In few invertebrates, presence of AhR has been reported in arthropods, nematodes, molluscs,

• Cellular senescence mediated by P involves multiple signalin

  2020-07-28

  

  Cellular senescence mediated by P53 involves multiple signaling pathways. However, how to regulate the Fmoc-Cl mg of P53 by CAE in fibroblasts was previously unexplored. Studies have shown that COX-2 was down-regulated in IPF patients and that its activity was required to exert an anti-fibrotic eff

• br Materials and methods br Results br

  2020-07-28

  

  Materials and methods Results Discussion Recently it has been found that prostaglandins play an important role in modulating the host immune system [1,3,22,23], and some parasites produce these eicosanoid mediators to survive into their hosts [6,[10], [11], [12],24,25]. The discovery that p

• br Materials and methods br Results br Discussion One novel

  2020-07-28

  

  Materials and methods Results Discussion One novel finding in our study is that CK2 inhibition preserved axon function and structure in WM against ischemia. Consistent with these findings, oligodendrocytes, astrocytes, myelin, and AS 101 were found to express CK2α. The robust expression pat

• br Model of receptor binding

  2020-07-28

  

  Model of receptor binding and activation It has been proposed that ETAs display an inactive conformation (R) or an active conformation (R*) that can bind one or more G proteins (G) and other mirtazapine high proteins (Figure 1a). An orthosteric agonist (e.g. ET1) binds sequentially and polyvalent

• In the gel shown in Figure at early

  2020-07-27

  

  In the gel shown in Figure 8, at early time-points, 14% of the input dsDNA is converted to these intermediate species. These persist in the gel to later times, with approximately 50% of these being unwound. This unwinding occurs at a considerably slower rate and is due to that fraction of the popula

• Here we used the ATDC cell line as a model

  2020-07-27

  

  Here we used the ATDC5 cell line as a model of endochondral proliferation and ossification. The miDdr2-transfected ATDC5 cell lines are useful models of precursor endochondral Bax inhibitor peptide V5 receptor because we found that they retained normal differentiation ability. DDR2 reduction induce

14988 records 814/1000 page Previous Next First page 上5页 811812813814815 下5页 Last page