• br Introduction In myasthenia gravis MG autoantibodies again

  2022-12-02

  

  Introduction In myasthenia gravis (MG), autoantibodies against the native AChR conformation cause loss of AChR at the neuromuscular junction and fatigable muscle weakness (Newsom-Davis et al., 1993). The AChR is a pentameric transmembrane protein, with two splice forms of the α-subunit, P3A− and

• Until now there are no report regarding

  2022-12-02

  

  Until now, there are no report regarding the relationship of CD21 and MG. In the present study, we aimed to characterize the AchR specified SKF 86002 dihydrochloride and investigated the role of CD21 in immunopathogenesis of MG. We utilized the Allophycocyanin (APC)-conjugated AchR to measure the f

• br Dihydrotestosterone in adult fish and frogs

  2022-12-02

  

  Dihydrotestosterone in adult fish and frogs New perspectives and next directions Similar to other androgens, DHT can modulate reproductive endpoints in both fish and amphibians. However, predicting the effects of DHT can be challenging, as reproductive homeostasis is dependent upon the balance

• Evidences have suggested that impairment of CK

  2022-12-02

  

  Evidences have suggested that impairment of CK activity contributes to inhibition of Na+, K+-ATPase and H+-ATPase activities during infectious diseases, since these ATPases are dependent of ATP, as observed by Baldissera et al. [31] in fish experimentally infected by Aeromonas caviae. We observed th

• br Perspective AA LA and other PUFAs and their

  2022-12-02

  

  Perspective AA, LA and other PUFAs and their lipid metabolites play an important role in human diseases. 12/15-LOX which is the metabolic enzyme of them plays an important role in the pathogenesis-related diseases such as atherosclerosis, diabetic nephropathy, neurological diseases and other path

• The apoptosis promoting Bcl family includes

  2022-12-02

  

  The apoptosis-promoting Bcl-2 family includes BH3-only proteins (e.g., Bim, Bid and Bad) and multiple-domain proteins (e.g., Bax and Bak). At the time of apoptosis stimulation (e.g., DNA damage), only the BH3-only protein is activated, directly or indirectly promoting Bax/Bak oligomerization, changi

• Chlorogenic acid an abundant polyphenol found in coffee

  2022-12-02

  

  Chlorogenic lipoxygenase inhibitor (7), an abundant polyphenol found in coffee and the human diet, has various biological activities including antioxidant and anticancer effects [54]. Jiang et al. reported that compound 7 had a selective cytotoxic activity on human oral tumor cells (HSG, HSC-2) as c

• Introduction According to Uganda s Ministry of Health

  2022-12-02

  

  Introduction According to Uganda's Ministry of Health (MOH 2012a:91), intermittent preventive treatment (IPT) to avoid malaria during pregnancy is a free preventive service available to all pregnant women without clinical signs and symptoms of malaria, attending prenatal clinics. However, pregnant

• br Removal of therapeutic doses of

  2022-12-02

  

  Removal of therapeutic doses of Tetrazole from Marek’s Disease Vaccines The impact of this change seems to vary widely among operations, probably dependent on the pre-existing quality of hatching egg production, hatchery sanitation, hatchery management, and brooding management. Increases in 7-da

• Tetracyclines constitute one of the most important

  2022-12-02

  

  Tetracyclines constitute one of the most important antibiotic groups used as veterinary and human medicine and as feed additives in the agricultural sector (Li et al., 2011a, Simon, 2005). Annual worldwide production of tetracyclines is estimated to be in the thousands of tons (Michalova et al., 200

• Given that the FST protocol

  2022-12-02

  

  Given that the FST protocol for mice does not engage the exposure to a previous stressful session, posits that Agtr1a levels could be kept higher by basal glutamatergic transmission rather than by stressful stimuli as postulated before. To address this possibility, we used the EMBL-EBI Expression At

• Recent retrospective cohort studies have

  2022-12-02

  

  Recent retrospective cohort studies have supported these preclinical findings in animals indicating the correlation of AR activation with the induction of AVE 0991 carcinogenesis. First, men with prostate cancer who underwent androgen deprivation therapy were shown to have a significantly lower ris

• br Expression of ADK in the normal brain In

  2022-12-01

  

  Expression of ADK in the normal brain In adult brain, ADK is primarily expressed in astrocytes. Immunocytochemical analysis of adult rat and mouse LY 255283 australia revealed predominant astrocytic expression throughout the hippocampus and cortex. Two isoforms of ADK have been identified in mam

• In pioneering work from Ikeda and

  2022-12-01

  

  In 2006, pioneering work from Ikeda and colleagues showed that GMF localizes to and regulates the NPS-2143 mg cytoskeleton (see Glossary), and noted its sequence similarity to ADF/cofilin[11]. In 2009, the structure of GMF [6] was solved, revealing it to be a bona fide member of the actin depolymeri

• BB-94 br Introduction The principal pathways of adrenal and

  2022-12-01

  

  Introduction The principal pathways of adrenal and gonadal steroidogenesis have been known for over 50 years (reviewed by Miller and Auchus, 2011). Cholesterol is first converted to pregnenolone via three reactions, 20-hydroxylation, 22-hydroxylation and scission of the 20,22 carbon–carbon bond,

14873 records 366/992 page Previous Next First page 上5页 366367368369370 下5页 Last page